By Steven Howard,Chris Abell,Harren Jhoti,Martin Drysdale,Daniel A Erlanson,Tony Giannetti,Isabelle Krimm,Michael Hann,Peter Kutchukian,Terry Hughes,Christina Spry,Iwan de Esch,Miles Congreve,Roderick Hubbard,Paul Bamborough
Fragment-based drug discovery is a swiftly evolving zone of analysis, which has lately noticeable new functions in components akin to epigenetics, GPCRs and the identity of novel allosteric binding wallet. the 1st fragment-derived drug was once lately authorized for the therapy of cancer. it truly is was hoping that this approval is simply the start of the numerous medicines but to be chanced on utilizing this attention-grabbing strategy.
This ebook is written from a Chemist's point of view and comprehensively assesses the effect of fragment-based drug discovery on a wide selection of components of medicinal chemistry. it is going to turn out to be a useful source for medicinal chemists operating in academia and undefined, in addition to someone drawn to novel drug discovery techniques.
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